All posts by Paleo Expert Dr.J.Bruno, M.B.,B.S., M.Ch.,

Dr.J.Mariano Anto Bruno Mascarenhas, M.B.,B.S., M.Ch., is a Brain Surgeon, Spine Surgeon and Neurosurgeon and Senior Assistant Professor of Neurosurgery. He did his Under graduation (MBBS) in Tirunelveli Medical College and Super Specialisation (MCh Neurosurgery) in Madras Medical College. He has bagged Gold Medal during his Education and was awarded the Best Paper Award by Neurological Society of India for his Research Paper. He has written more than a dozen books in English and Tamil regarding Medicine and Healthcare. He is an active participant in discussion involving the science of Low Carbohydrate Diet in Media and Social Media.

Will Low Carb High Fat Diet Increase Blood Urea Levels and Cause Kidney Failure

Will Low Carb High Fat Diet Increase Blood Urea Levels and Cause Kidney Failure

இந்த கட்டுரையின் தமிழ் வடிவம் குறைமாவு நிறைகொழுப்பு உணவு சாப்பிட்டால் யூரியா கூடி சிறுநீரகம் பாதிப்பு ஏற்படுமா ? என்ற பக்கத்தில் உள்ளது



-oOo-

  • Those who undergo Blood Investigations after few weeks of Low Carbohydrate High Fat diet are alarmed at increased in Blood Urea Levels as compared to previous test results.
  • Those who are aware that Blood Urea Level Increases in Kidney Failure immediately get terrified and start to doubt whether their diet has affected the kidneys

Of course, when there is Renal Failure (i.e. Kidneys do not function properly), The Urea Level in Blood Increases
But
Renal Failure is not the only cause of Increase in Blood Urea Levels

Let us discuss this issue in detail in this article

-oOo-

Will Low Carb High Fat Diet Increase Blood Urea Levels and Cause Kidney Failure ?
Will Low Carb High Fat Diet Increase Blood Urea Levels and Cause Kidney Failure ?
  • Proteins in food  are broken down into Urea
  • Urea has to be excreted
  • Accumulation of Urea in Blood will affect Organs like Brain
  • Urea is excreted by Kidneys

-oOo-

The amount of Urea synthesised and the Amount of Urea Excreted are constant and hence urea level is maintained

Urea Level in Blood increases if

  1. More Urea is Synthesised
  2. Less Urea is Excreted

-oOo-

  • More Urea is Synthesised when More Proteins are taken
  • Less Urea is Excreted when Kidneys do not function properly

-oOo-

Urea Level in Blood increases if

  1. More Proteins are Taken
  2. Kidneys do not function properly

Urea in Blood is also increased in

  1. Salt and Water Depletion
  2. Vomiting
  3. Diarrhea
  4. Haemetemesis
  5. Hemorrhage
  6. Ulcerative Colitis
  7. Addison’s disease
  8. Acute Glomerulonephritis
  9. Type II Nephritis
  10. Malignant Nephrosclerosis
  11. Pyelonephritis
  12. Mercury Poisoning
  13. Hydronephrosis
  14. Renal Tuberculosis
  15. Renal Calculi
  16. Prostate enlargement
  17. Tumours of Urinary Tract

-oOo-

So

Kidneys are not affected by Low Carbohydrate High Fat Diet
But
When there is a pre existing Renal Failure (there is already kidney failure), the increased urea can affect organs like brain (uremic encephalopathy)

-oOo-

Which Food Has More Chance of Affecting Kidney
A Food with hIgh carbs has more chance of affecting kidney

-oOo-

Which Food has less chance of Affecting Kidney
A Low Carb High Fat Diet has Less Chance of Affecting Kidney

-oOo-

To Put it in a nutshell,
Start Low Carbohydrate High Fat Diet or Paleo Diet and save your kidneys before they are damaged by High Carbohydrate Diet

Do you have evidence for this ?

Yes ! Please see

  1. Comparative effects of low-carbohydrate high-protein versus low-fat diets on the kidney by Friedman AN, Ogden LG, Foster GD, Klein S, Stein R, Miller B, Hill JO, Brill C, Bailer B, Rosenbaum DR, Wyatt HRin Clin J Am Soc Nephrol. 2012 Jul;7(7):1103-11. doi: 10.2215/CJN.11741111. Epub 2012 May 31. who conclude that In healthy obese individuals, a low-carbohydrate high-protein weight-loss diet over 2 years was not associated with noticeably harmful effects on GFR, albuminuria, or fluid and electrolyte balance compared with a low-fat diet. Further follow-up is needed to determine even longer-term effects on kidney function.
  2. A low-carbohydrate diet may prevent end-stage renal failure in type 2 diabetes. A case report by Jørgen Vesti Nielsen,  Per Westerlund, and Per Bygren in Nutr Metab (Lond). 2006; 3: 23. Published online 2006 Jun 14. doi: 10.1186/1743-7075-3-23 PMCID: PMC1523335 state that An obese patient with type 2 diabetes whose diet was changed from the recommended high-carbohydrate, low-fat type to a low-carbohydrate diet showed a significant reduction in bodyweight, improved glycemic control and a reversal of a six year long decline of renal function. The reversal of the renal function was likely caused by both improved glycemic control and elimination of the patient’s obesity. Insulin treatment in type 2 diabetes patients usually leads to weight increase which may cause further injury to the kidney. Although other unknown metabolic mechanisms cannot be excluded, it is likely that the obesity caused by the combination of high-carbohydrate diet and insulin in this case contributed to the patient’s deteriorating kidney function. In such patients, where control of bodyweight and hyperglycemia is vital, a trial with a low-carbohydrate diet may be appropriate to avoid the risk of adding obesity-associated renal failure to already failing kidneys.
  3. Reversal of Diabetic Nephropathy by a Ketogenic Diet by Michal M. Poplawski, Jason W. Mastaitis, Fumiko Isoda, Fabrizio Grosjean, Feng Zheng, Charles V. Mobbs Published on April 20, 2011 in http://dx.doi.org/10.1371/journal.pone.0018604 conclude Intensive insulin therapy and protein restriction delay the development of nephropathy in a variety of conditions, but few interventions are known to reverse nephropathy. Having recently observed that the ketone 3-beta-hydroxybutyric acid (3-OHB) reduces molecular responses to glucose, we hypothesized that a ketogenic diet, which produces prolonged elevation of 3-OHB, may reverse pathological processes caused by diabetes. To address this hypothesis, we assessed if prolonged maintenance on a ketogenic diet would reverse nephropathy produced by diabetes. In mouse models for both Type 1 (Akita) and Type 2 (db/db) diabetes, diabetic nephropathy (as indicated by albuminuria) was allowed to develop, then half the mice were switched to a ketogenic diet. After 8 weeks on the diet, mice were sacrificed to assess gene expression and histology. Diabetic nephropathy, as indicated by albumin/creatinine ratios as well as expression of stress-induced genes, was completely reversed by 2 months maintenance on a ketogenic diet. However, histological evidence of nephropathy was only partly reversed. These studies demonstrate that diabetic nephropathy can be reversed by a relatively simple dietary intervention. Whether reduced glucose metabolism mediates the protective effects of the ketogenic diet remains to be determined.

Feel Free to ask doubts

-oOo-

Acknowledgements

  1. Dr.Arunkumar M.B., B.S., M.D., (Paediatrics) KMCH Erode for Journals



Basis of Paleo : How Fat Dissolves and What happens to that Fat that dissolves ?

Basis of Paleo : How Fat Dissolves and What happens to that Fat that dissolves ?

இந்த கட்டுரையின் தமிழ் வடிவம் மாவுச்சத்து குறைவாக சாப்பிடுவதால் கொழுப்பு எப்படி கரைகிறது; கரைந்த கொழுப்பு என்னவாகிறது ? என்ற பக்கத்தில் உள்ளது



-oOo-

I am not afraid of change. I am more afraid of staying the same
– Joseph Roy Fredericks

The Fat in your body is not constant. It changed. It changes. And it will Change.  Change every day, every hour, every minute and every second. At any given moment, new fat is made and a part of fat gets degraded

Now image the overhead tank in your house. It has an inflow from Well or Underground Water Sump. And the overhead tank has an outflow of water to various rooms in your home

  • If the inflow into the tank matches the outflow, then the level of water will be constant.
  • If the inflow is greater than the outflow, then the level of water will increase.
  • If the inflow is lesser than the outflow, then the level of water will decrease.

Same way, Coming back to fat

  • If the amount of fat synthesized is equal to the amount of fat degraded, then the fat in your body will be constant
  • If the amount of fat being made is greater than the amount of fat being broken, then you will keep on gaining weight and become obese.
  • If the amount of fat being made is lesser than the amount of fat being broken, then you will keep on losing weight and become lean.

The Fats / Lipids in Body exist in two forms

  1. Element Constant of Structural Lipids. These form the various structures and are relatively constant. These are mainly phospholipids
  2. Element Variable or stored Lipids or Depot. These are mainly used for Fat Storage and the amount of this varies as per the food and need. These are Mainly Triglycerides. These are the ones which get deposited in your belly and gluteal region and in other regions making you obese

How are Triglycerides Made

Triglycerides are made from two components

  1. Free Fatty Acids : These are derived from the Fat as well as from Carbohydrates in the food
  2. Glycerol Phosphate : These are derived from the Carbohydrate in Food

So, to make Triglycerides, you need either Fat + Carbs or Carbs Alone. With Fat alone, little Triglycerides are synthesised. 

The process of synthesis of Triglycerides (aka Belly and Buttocks Fat) is supported by few hormones and opposed by few hormones

Insulin Supports this synthesis

How are Triglycerides Broken

Triglycerides are broken to Glycerol Phosphate and Free Fatty Acid by an enzyme called Hormone Sensitive Triglyceride Lipase. This action is inhibited by Insulin and favoured by

  1. Epinephrine
  2. Norepinephrine
  3. Glucagon
  4. Growth Hormone
  5. Glucocorticoids
  6. ACTH
  7. MSH
  8. TSH
  9. Vasopressin

Effect of Insulin

Insulin favours Formation of Triglycerides. Insulin Opposes Breaking down of Triglycerides. Insulin favours formation of adipose tissue and inhibits breakdown of adipose tissue. In Short, Insulin leads to a person becoming obese, gaining wait

What happens in Carbohydrate Rich Food

When the food is rich in Carbohydrates,

  1. More Glycerol Phosphate is formed. More Substances to form Fat
  2. More Free Fatty Acids are formed
  3. More Insulin is secreted by Pancreas. More Stimulus for Fat Formation. Less Stimulus for Fat Breakdown

All these three act to create more and more fat or adipose tissue and the person becomes obese, even if he does not take fat in his meal

In short, during Carbohydrate Rich Food, the rate of formation of fat is higher than the rate of destruction of fat, leading to net increase of fat in the body



What happens in Low Carbohydrate High Fat Food

When  the food does not have Carbohydrates or when the food has low Carbohydrates

  1. Less Glycerol Phosphate is formed. Hence there is less substance needed formation of fat
  2. Less Insulin Secretion. Hence less stimulation for Fat Formation
  3. Less Insulin Secretion. So there is more breakdown of fats by the hormones like Epinephrine, Norepinephrine, Glucagon, Growth Hormone, Glucocorticoids, ACTH, MSH, TSH, Vasopressin

So, in short, during a Low Carbohydrate diet, the formation of fat is very less, but destruction (degradation or lipolysis) of fat is accelerated leading to net loss of fat in the body. Hence people lose weight and also the fat stores in their abdominal wall and gluteal region begin to disappear

What happens to the Fat that is broken down

The Fat is broken down into Glycerol Phosphate and Free Fatty Acids. Of this

  1. Glycerol Phosphate can be converted to Dihydroxy acetone Phosphate and this can be converted to Glyceraldehyde Phosphate which is an intermediary in the breakdown of Glucose.  Hence this enters the Glycolytic Pathway.  So, even though there is no Glucose in the diet, there is an element which enters the Glycolytic pathway during LCHF Meal.
  2. The Fatty Acids are used to Generate Energy




Scientific Basis of Paleo
Scientific Basis of Paleo

Why More Fat is Needed in Paleo Diet ? Why you should not Reduce Fat Intake ?

Why More Fat is Needed in Paleo Diet ? Why you should not Reduce Fat Intake ?

இந்த கட்டுரையின் தமிழ் வடிவம் மாவு சத்து, கொழுப்பு சத்து இரண்டையுமே குறைத்து சாப்பிட்டால் என்ன ? என்ற பக்கத்தில் உள்ளது


Many people have the following doubts regarding Paleo Diet or Low Carb High Fat Diet

  • Why can’t we reduce both Fat as well as Carbs
  • Why we have to reduce only carbs
  • Why you don’t recommend to reduce fats

The Answer is Simple

-oOo-

Body Needs Energy to Function

This Energy can be got from Carbs or from Fat, but it has to be got from either on of the above (or else there will be protein denaturation leading to Starvation and Finally death)

Because Energy is needed, We have to increase Fat intake when we reduce Carbs Intake

-oOo-

When you can get the energy from both Carbs as well as Fat, why are fats preferred and why not Carbs

The Answer is Simple

When we wat, the energy in our food

  1. Is Spend (or used)
  2. Is Stored

But, Nature has some surprises for you. The two main surprises are

  1. Whatever form of Energy you intake, whatever source from which it is obtained, it is stored as fat. Whether you take Carbs in Excess or Fat in Excess, it is stored as Fat
  2. The amount of Energy that has to be stored and the amount of energy that has to be utilised is determined by the amount of Carbs we intake

In Short,
It is the amount of Carbs in our food determines the amount of fat that gets stored in the body
Let me repeat it again
It is the amount of Carbs in our food determines the amount of fat that gets stored in the body, in the abdomen, inside the blood vessels

So

  • Even if you take Only Carbs and Avoid taking fats altogether, there will be still fat deposition in your body
  • If you taken both carbs as well as fats, there will be fat deposition in your body
  • If you take Low Carbs and High Fats, most of these will be used and very very less will be stored. This is why those with Low Carb High Fat Diet (LCHF Diet) reduce weight and become lean
  • If you take low carbs and low fats, body does not have enough source of energy. Hence body enters Catabolic Phase and the proteins are broken down, denatured and the amino acids are deaminated and they enter the Citric Acid Cycle to give energy. This will lead to muscle wasting,  and left unchecked, even death

-oOo-

Low Carb High Carb Low Fat High Fat Obesity Starvation Paleo
Low Carb High Carb Low Fat High Fat Obesity Starvation Paleo

-oOo-

உடல்பருமன், பசி, பேலியோ
உடல்பருமன், பசி, பேலியோ

-oOo-

Paleo, Starvation, Well Fed, High Carb, Low Carb, High Fat, Low Fat
Paleo, Starvation, Well Fed, High Carb, Low Carb, High Fat, Low Fat



Reduced Insulin Secretion in Paleo Diet : Complications ?

Reduced Insulin Secretion in Paleo Diet : Complications ?

இந்த கட்டுரையின் தமிழ் வடிவம் பேலியோவால் இன்சுலின் சுரப்பது குறைவதால் பாதிப்புகள் ஏற்படுமா என்ற பக்கத்தில் உள்ளது



-oOo-

Few Questions come up when we discuss Low Carbohydrate High Fat Diet (Paleo Diet, Atkins Diet etc)

Question 1
But, Dr Mariano Anto Bruno Mascarenhas , my doubt is as insulin is a very important anabolic hormone and plays a very vital role in protein synthesis from amino acids , won’t the decreased insulin also lead onto less protein production and more proteolysis?
Question 2
If we don’t eat Carbohydrates, Insulin Secretion will decrease. Will the Pancreas stop secreting insulin altogether ?
Question 3
Can Pancreas Stop Secreting Insulin if we take Low Carb

Let us explain about this concept in this article

-oOo-

You must have known that Insulin is a hormone Secreted by Beta Cells of Pancreas and from There, insulin is directly released into the blood. After getting released into blood, insulin does the following metabolic activities

  1. Increases Glucose Uptake
  2. Increases Glycolysis
  3. Increases conversion of Pyruvate to Acetyl CoA
  4. Increases Glycogenesis
  5. Decreases Glycogenolysis
  6. Decreases Gluconeogenesis
  7. Increases HMP Shunt
  8. Decrease Lipolysis
  9. Increase Fatty Acid Synthesis
  10. Increases TriGlycerides Synthesis
  11. Decreases Ketogenesis
  12. Increase Amino Acid uptake
  13. Protein Anabolic Effect of Growth Hormone (permissive effect)
  14. Increases protein Synthesis
  15. Regulation of Ribosomal Translation
  16. Decrease in Potassium and Phosphorus in Blood
  17. Stimulates Growth and Cell Replication

-oOo-



From this extremely long list, we can know that reduction in blood Glucose is the main function of Insulin. The Main Function of Insulin is Anabolism and Reduction of Insulin is just the side effect of that. 

In fact

  • The number of hormones which reduce blood glucose (like insulin) is quite low
  • There are a huge nunber of hormones which increase the glucose in blood

Why? Because

  • Our Body is inherently not suited to eat Carbohydrates
  • We are inherently suited to eat fats
  • Since we are not supposed to eat Carbs, Nature has given us only insulin to deal with Glucose in Blood and lots of other hormones to deal with fat
  • That is why lack of a single hormone which has to reduce blood sugar leads to disease
  • When one of the hormones which has to increase blood sugar is not functioning properly, the other hormones take the role and hence the person does not become diseased

In Human Evolution, Our Food Pattern Changed to Predominatly Carb just recently

  • That is after we started regular Agriculture and Cultivation
  • That is in the past 2000 years

-oOo-

And, when our body is not suited for Carbohydrates, we take a predominantly Carbohydrate Food. What Will happen

  • Glucose Level in Blood Increases
  • Insulin is the only hormone which has to fight this
  • Insulin Secretion Increases beyond its physiological capacity

What will happen when insulin secretion in kept at a high level for months and years together
-oOo-

Assume a Village with 50 families and a Village Pond which feeds them

The water in the village pond is sufficient for 50 families

What will happen when a Water Bottling Company comes and sets up the factory and uses Bore Well to get all the water

The Pond will become Dry Soon. . .Isn’t it

-oOo-



In the same way, When we eat more Carbohydrates than what we are supposed to eat

  • Lots of Insulin is Needed
  • Lots of Insulin is secreted
  • Over a period of time, the beta cells get tired
  • and
  • At this stage, the patient is given tablets to increase the secretion

After this time, beta cells wear down (the pond is even more drier)

  • We need to give Insulin by Injection

-oOo-

When the Pond is totally dry, The Village is dependant on Water Coming inside in Lorries

-oOo-

If we don’t eat More Carbs, the amount of Insulin needed is less and our Pancreas and beta cells do not get tired 

-oOo-

We all know that each and every village pond is different. Not All Ponds are the same

  • Some Ponds can support only 50 families
  • Some Ponds have more water and can support even 100 families
  • Some Ponds have even more Water and can even support a Bottling Factory

-oOo-

Same Way, each and every one’s pancreas has different capacity

  • Many people’s pancreas can tolerate only limited Carbohydrates. When this level is crossed, the beta cells cannot cope up
  • Few others have a pancrease which can tolerate more carbohydrates for some time alone, but after that the beta cells get tired and reduce the secretion
  • Few others are blessed with a pancreas that can tolerate any amount of insulin

-oOo-

Of this

  • The First Category belongs to Type 2 Diabetes Mellitus (Type 2 DM)
  • The Second Category belongs to Pre Diabetes or Impaired Glucose Tolerance என்கிறோம்
  • The Third Category do not become diabetic even after eating kilos of sweets

-oOo-

நீரிழிவு நோய் நிலைகள்
நீரிழிவு நோய் நிலைகள்

So, what is meant by Type 1 Diabetes Mellitus (Type 1 DM)

  • If the Pond dries up since lots of water has been pumped out, it is Type 2 DM
  • If there was a war in the area of pond, the pond becomes unusable. That is ype 1 DM

That’s All Folks !

Tests to be Done Before Starting Low Carb High Fat Diet

Tests to be Done Before Starting Low Carb High Fat Diet
இந்த கட்டுரையின் தமிழ் வடிவம் குறைந்த மாவுச்சத்து உணவினை உண்பதற்கு முன் செய்ய வேண்டிய பரிசோதனைகள் என்ற பக்கத்தில் உள்ளது


-oOo-

Before you start Low Carbohydrate High Fat Diet, we need to know what all you can take and what all you have to avoid

For this, a series of Blood Tests are needed. If you are in Chennai, You can call +91 86680 28312 for Home Collection or
Do in nearby lab if it is cheaper You can do it any where
*Coagulation Profile*
  • PT
  • INR
  • aPTT
*CARDIAC RISK MARKERS (5)* 
  • APOLIPOPROTEIN – B (APO-B)
  • APO B / APO A1 RATIO (APO B/A1)
  • LIPOPROTEIN (A) [LP(A)]
  • HIGH SENSITIVITY C-REACTIVE PROTEIN (HS-CRP)
  • APOLIPOPROTEIN – A1 (APO-A1)
*DIABETES (2)* 
  • HbA1c
  • AVERAGE BLOOD GLUCOSE (ABG)
*HORMONE (1)* 
  • TESTOSTERONE
*IRON DEFICIENCY (3)* 
  • TOTAL IRON BINDING CAPACITY (TIBC)
  • % TRANSFERRIN SATURATION
  • IRON
*LIPID (8)* 
  • LDL / HDL RATIO
  • NON-HDL CHOLESTEROL
  • LDL CHOLESTEROL – DIRECT
  • VLDL CHOLESTEROL
  • TC/ HDL CHOLESTEROL RATIO
  • TOTAL CHOLESTEROL
  • HDL CHOLESTEROL – DIRECT
  • TRIGLYCERIDES
*LIVER (11)* 
  • ALANINE TRANSAMINASE (SGPT)
  • SERUM GLOBULIN
  • GAMMA GLUTAMYL TRANSFERASE (GGT)
  • BILIRUBIN – TOTAL
  • BILIRUBIN -DIRECT
  • BILIRUBIN (INDIRECT)
  • ALBUMIN – SERUM
  • ASPARTATE AMINOTRANSFERASE (SGOT )
  • SERUM ALB/GLOBULIN RATIO
  • PROTEIN – TOTAL
  • ALKALINE PHOSPHATASE
*KIDNEY (5)* 
  • BLOOD UREA NITROGEN (BUN)
  • CALCIUM
  • URIC ACID
  • BUN / Sr.CREATININE RATIO
  • CREATININE – SERUM
*THYROID (3)* 
  • TOTAL TRIIODOTHYRONINE (T3)
  • TOTAL THYROXINE (T4)
  • THYROID STIMULATING HORMONE (TSH)
*VITAMIN (2)* 
  • 25-OH VITAMIN D (TOTAL)
  • VITAMIN B-12
*COMPLETE HEMOGRAM*
  • HEMOGLOBIN
  • TOTAL RBC
  • PLATELET COUNT
  • IMMATURE GRANULOCYTES(IG)
  • IG%
  • NEUTROPHILS – ABSOLUTE
  • LYMPHOCYTES – ABSOLUTE
  • MONOCYTES – ABSOLUTE
  • EOSINOPHILS – ABSOLUTE
  • BASOPHILS – ABSOLUTE
  • BASOPHILS
  • EOSINOPHILS
  • TOTAL LEUCOCYTES COUNT
  • LYMPHOCYTE PERCENTAGE
  • MONOCYTES
  • NEUTROPHILS
  • NUCLEATED RBC
  • NUCLEATED RBC%
  • HEMATOCRIT(PCV)
These are available as a Packages from Thyrocare / Aarthi Scans / Orbitoasia etc. Chose the appropriate packages
  • If you have already done this, please send us the reports
  • If you have not done this, please do it

You can also communicate to the Lab by Whatsapp
Ask Clarification from Doctor in this Whatsapp Number 9940626911



Impotence, Erection Problems, Premature Ejaculations, Sterility : Paleo

Impotence, Erection Problems, Premature Ejaculations, Sterility : Paleo

இந்த கட்டுரையின் தமிழ் வடிவம் ஆண்மைக்குறைவு, ஆண் மலட்டுத்தன்மை சிகிச்சை : பேலியோ என்ற பக்கத்தில் உள்ளது



-oOo-

  • Male Hormon is Testosterone
  • Female Hormone is Estrogen

Testosterone is required for Male Attributes as well as for Sperm Production.When Testosterone is reduced in Blood, it can lead to

  • Impotence : The individual cannot have sex in proper way
  • Sterility. The individual cannot have a child

-oOo-

The reasons for Low testosterone in blood are 

  1. Decreased synthesis
  2. Increased degradation

-oOo-

When a person is having impotence, problems in erection or sterility due to low testosterone, it can be treated in three ways

  1. Production can be Increased
  2. Degradation can be reduced
  3. Testosterone can be given from outside through injections

-oOo-

How is Testosterone degraded?

In the Fat Cells (Adipose Tissue) of our body (as well as in few other cells) there is an Enzyme called Aromatase. This enzyme Converts Testosterone into Estrogen

In Short

When there is more fat in a person’s body, more of his testosterone are converted to estrogen

-oOo-

What are the Functions of Estrogen ?
Estrogen increases Fat Synthesis. In fact Estrogen and Insulin are the two main hormones which increase fat synthesis

In Short Estrogen Increases Fat. This increased Fat converts more testosterone into more oestrogen. And that more Oestrogen gives more more fat and that more more fat give more more oestrogen and a vicious cycle is formed due to positive feedback

Fat –> Oestrogen –> More Fat –> More Oestrogen –> more more fat –> More More Oestrogen –> more more more fat –> more more more oestrogen
Testosterone Decreases in High Carbohydrate Diet
In Short, because of more fat in the body

  1. Fat further increases
  2. Oestrogen Further increases
  3. Testosterone further decreases

-oOo-



Over a period of time, the individual feels the effects of low testosterone and consults a doctor and gets testosterone injection. But when there is more fat in the body, this soon gets converted to estrogen and hence more dose is needed

-oOo-

The problem can be also tackled in a different way. Of the three ways which are available

  • Production can be Increased
  • Degradation can be reduced
  • Testosterone can be given from outside through injections

We can solve this problem very easily by reducing the degradation of testosterone

-oOo-

How to reduce the Degradation ?
By Reducing the Fat in the Body

-oOo-

How to Reduce the Fat in the body ?
By Reducing the Amount of Insulin in Blood

-oOo-

How to reduce the Amount of Insulin in Blood ?
By Reducing the Amount of Carbohydrates in Blood

-oOo-

How to reduce the Carbohydrates in Blood ?
By Following Paleo Diet

-oOo-

In Short

The amount of Testosterone in Blood will increase If you follow Paleo Diet

-oOo-

Now, you may have few doubts

  • Is Impotence and Sterility the same
  • If Not, what is the difference
  • Will a person lose his potency if he undergoes Family Planning Operation

Let us see this too

-oOo-



Potency is based on the capacity of a male to indulge is sex. Based on this, a person can be

  • Potent : Can Indulge in Sex
  • Impotent : Have Problems during Sex

-oOo-

Same way, depending on whether one can beget a child or not, there are two conditions

  • Can beget a child – Fertility
  • Cannot beget a child  – Sterility

-oOo-

These two are distinct classifications

For example
Take two colors : Black and White
Take two objects : Pen and Pencil
Now you can have four combinations, viz

  • Black Pen
  • White Pen
  • Black Pencil
  • White Pencil

Same way, with Potency, Impotency, Sterilty, Fertility,  We have four combinations

  • Potent and Fertile : Can Have Sex. Can Have Children
  • Impotent and Fertile : Problems in Sex. Can Have Children
  • Potent, but sterile (infertility) : Can have Sex. Cannot have children
  • Impotent, Sterile (infertility) : Cannot have Sex. Cannot have children

-oOo-

Potency, Fertility

  • Most Males are in this category

Impotency, Fertility

  • Many are in this category.
  • This can be due to many reasons
  • Most such causes are curable
  • If the problem is due to Psychological reasons, Placebos can help

Potency, Infertility (Sterility)

  • This is an important category
  • Many people don’t know that this category exists
  • Most males assume that they wont have any problem with fertility, if they are potent
  • Few of these conditions are treatable. Few are not treatable

Please note : Those who undergo Male Sterilisation like Vasectomy come in this category. Vasectomy will NOT Affect Potency

Impotency, Infertility

This can be due to various diseases

Causes and Natural Treatment of Obesity and Overweight

Causes and Natural Treatment of Obesity and Overweight

இந்த கட்டுரையின் தமிழ் வடிவம் உடல் பருமன் : காரணங்கள் மற்றும் தீர்வுகள் என்ற பக்கத்தில் உள்ளது



-oOo-

Obesity or Overweight can be due to four main causes

1. Primary Genetic Insulin Resistance
2. Not doing physical work and being the so called couch potato (Sedantary Life Style)
3. Diseases Related to Fat metabolism (Dyslipidaemias)
4. Eating Too Much. (also called Gluttony)

-oOo-

Of these,

If your Obesity and Overweight is due to Sedentary Life Style, you can reduce your weight and waist circumference by Walking, Jogging, Running, Swimming, Cardio, Lifting Weights etc
If your Obesity and Overweight is due to eating too much, you can reduce your weight and excess fat by eating less
If your Obesity and Overweight is due to Dyslipidaemias, you can reduce your weight and excess fat by appropriate treatment

But

If your Obesity and Overweight is due to Primary Genetic Insulin Resistance, the only way you can reduce weight is by taking Low Carbohydrate Diet. Running Miles in Treadmill or Starvation will not solve your problem

-oOo-

Causes of Obesity and Solutions

-oOo-

There was an extremely Wise Man who was searching for something in the park
A passerby enquired as to what he is searching
Our Wise Man told that he is searching for a hundred Rupee note
Since there was nothing there, the passerby again asked whether the note was lost here
Our Wise Man Replied that the note was lost in his home
Intrigued, the passerby asked as to Why he is searching the note in the park, while he had lost it in home
Oru Wise Man Replied that others are searching here and so he too would like to follow a balanced approach

-oOo-

This story is dedicated to All the Wise Man, who believe that they can correct the obesity due to Insulin Resistance by Eating Carbs and then Doing Exercises or by just reducing overall food intake leading to ketosis


Why More Fat is Needed in Paleo Diet ? Why you should not Reduce Fat Intake ?

Why More Fat is Needed in Paleo Diet ? Why you should not Reduce Fat Intake ?

இந்த கட்டுரையின் தமிழ் வடிவம் மாவு சத்து, கொழுப்பு சத்து இரண்டையுமே குறைத்து சாப்பிட்டால் என்ன ? என்ற பக்கத்தில் உள்ளது



Many people have the following doubts regarding Paleo Diet or Low Carb High Fat Diet

  • Why can’t we reduce both Fat as well as Carbs
  • Why we have to reduce only carbs
  • Why you don’t recommend to reduce fats

The Answer is Simple

-oOo-

Body Needs Energy to Function

This Energy can be got from Carbs or from Fat, but it has to be got from either on of the above (or else there will be protein denaturation leading to Starvation and Finally death)

Because Energy is needed, We have to increase Fat intake when we reduce Carbs Intake

-oOo-



When you can get the energy from both Carbs as well as Fat, why are fats preferred and why not Carbs

The Answer is Simple

When we wat, the energy in our food

  1. Is Spend (or used)
  2. Is Stored

But, Nature has some surprises for you. The two main surprises are

  1. Whatever form of Energy you intake, whatever source from which it is obtained, it is stored as fat. Whether you take Carbs in Excess or Fat in Excess, it is stored as Fat
  2. The amount of Energy that has to be stored and the amount of energy that has to be utilised is determined by the amount of Carbs we intake

In Short,
It is the amount of Carbs in our food determines the amount of fat that gets stored in the body
Let me repeat it again
It is the amount of Carbs in our food determines the amount of fat that gets stored in the body, in the abdomen, inside the blood vessels

So

  • Even if you take Only Carbs and Avoid taking fats altogether, there will be still fat deposition in your body
  • If you taken both carbs as well as fats, there will be fat deposition in your body
  • If you take Low Carbs and High Fats, most of these will be used and very very less will be stored. This is why those with Low Carb High Fat Diet (LCHF Diet) reduce weight and become lean
  • If you take low carbs and low fats, body does not have enough source of energy. Hence body enters Catabolic Phase and the proteins are broken down, denatured and the amino acids are deaminated and they enter the Citric Acid Cycle to give energy. This will lead to muscle wasting,  and left unchecked, even death

 



-oOo-

Paleo, Starvation, Well Fed, High Carb, Low Carb, High Fat, Low Fat
Paleo, Starvation, Well Fed, High Carb, Low Carb, High Fat, Low Fat

-oOo-

-oOo-